Treatment of necrobiosis lipoidica with combination Janus kinase inhibition and intralesional corticosteroid

Necrobiosis Lipoidica

Background: In 1929, Oppehhein first described necrobiosis lipoidica diabeticorum and called it dermatitis atrophicans lipoidica diabetica, but it was later renamed necrobiosis lipoidica diabeticorum (NLD) by Urbach in 1932. In 1935, Goldsmith reported the first case in a nondiabetic patient. Other cases of NLD in nondiabetic patients were described by Meischer and Leder in 1948. Rollins and Wi...

Necrobiosis Lipoidica: Early Diagnosis and Treatment with Tacrolimus

We present a case of necrobiosis lipoidica (NL) with atypical early lesions and good response to topical tacrolimus. NL is a disease with clinical features that are seldom misinterpreted. Often histology just confirms the clinician's diagnosis. Only in rare cases, the clinical presentation and the involved body sites may be misleading. A 67-year-old diabetic woman was admitted to our department...

Necrobiosis lipoidica

A 47-year-old woman reported an 18-month-old pretibial rash on her left shin during a routine office visit. She had a history of type 1 diabetes mellitus (DM) and has been on insulin therapy for the past 13 years. She did not complain of any itching, pain, or bleeding from the rash. On examination, an 8 3 cm elongated indurated plaque with telangiectases, central atrophy, and yellow pigmentatio...

Dermoscopy of Necrobiosis Lipoidica

5. Van Esso DL. Los padres frente a la vacunación. Vacunas. 2010;11:133--4. 6. Jiménez Gómez N, Ballester Martínez MA, Alcántara González J, Jaén Olasolo P. Koplik spots as a diagnostic clue in a case of measles. Med Clin (Barc). 2012;139:560. 7. Lefebvre N, Camuset G, Bui E, Christmann D, Hansmann Y. Koplik spots: a clinical sign with epidemiological implications for measles control. Dermatolo...

Necrobiosis lipoidica diabeticorum.